Description

10,11-Dihydro-10-[2-(Dimethylamino)Ethyl]-8-Methoxy-5H-Dibenzo[B,E][1,4]Diazepin-11-One is a high-purity, complex heterocyclic compound that serves as a critical intermediate in advanced pharmaceutical synthesis. Its precise molecular architecture makes it an essential building block for the development of active pharmaceutical ingredients (APIs) targeting the central nervous system. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel psychotropic and neuroactive drug candidates.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct intricate dibenzodiazepine-based molecular frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions and biochemical pathways related to its structural class.

Basic Information

Product Name	10,11-Dihydro-10-[2-(Dimethylamino)Ethyl]-8-Methoxy-5H-Dibenzo[B,E][1,4]Diazepin-11-One
CAS No.	1668-66-2
Molecular Formula	C19H21N3O2
Molecular Weight	323.39 g/mol
Synonyms	10,11-Dihydro-10-(2-dimethylaminoethyl)-8-methoxy-5H-dibenzo[b,e][1,4]diazepin-11-one; 8-Methoxy-10-(2-dimethylaminoethyl)-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one; Lofepramine Impurity; Lofepramine Related Compound; 1668-66-2; 10-(2-Dimethylaminoethyl)-8-methoxy-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-10-[2-(Dimethylamino)Ethyl]-8-Methoxy-5H-Dibenzo[B,E][1,4]Diazepin-11-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.