Description

5-Fluorophthalic Acid is a high-purity fluorinated aromatic dicarboxylic acid building block, essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs). Its unique structure, featuring both a carboxylic acid group and a fluorine atom on the phthalic acid backbone, makes it a critical intermediate for introducing fluorinated moieties into target molecules, enhancing their properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors seeking to develop novel compounds with improved metabolic stability, bioavailability, or material characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and diagnostic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atom improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a comonomer to create specialty polyesters, polyamides, and epoxy resins with enhanced thermal stability and chemical resistance.
• Metal-Organic Framework (MOF) Synthesis: Acts as a functionalized linker to construct porous materials for gas storage, separation, and catalysis.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating novel chemical entities.

Basic Information

Product Name	5-Fluorophthalic Acid
CAS No.	1583-66-0
Molecular Formula	C8H5FO4
Molecular Weight	184.12 g/mol
Synonyms	5-Fluorobenzene-1,2-dicarboxylic Acid; 4-Fluorophthalic Acid; 1,2-Benzenedicarboxylic Acid, 5-Fluoro-; 5-Fluoroisophthalic Acid (common misnomer); 5-Fluoro-1,2-benzenedicarboxylic Acid; 5-Fluorophthalsäure (German); Acide 5-fluorophtalique (French)
EINECS	216-418-5

Quality Control

Our 5-Fluorophthalic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	210°C - 215°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.