Quinolones

Synthetic Anti-Infective Drugs

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Quinolones

Quinolones are synthetic broad-spectrum antibacterial agents that exert their activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. These drugs, including ciprofloxacin, levofloxacin, moxifloxacin, and ofloxacin, demonstrate potent bactericidal effects against Gram-negative organisms and enhanced activity against Gram-positive pathogens in newer generations. Their excellent tissue penetration and oral bioavailability make them widely used for respiratory infections, urinary tract infections, gastrointestinal infections, bone and joint infections, and certain cases of sepsis. However, concerns such as tendinopathy, QT prolongation, CNS effects, and emerging resistance require careful prescribing. Despite these limitations, quinolones remain cornerstone therapeutics in many clinical settings due to their broad spectrum, rapid onset, and versatile dosing options.

Ecenofloxacin CAS NO 162301-05-5

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CAS No.:162301-05-5

Grade:Pharmacy Grade

Content:99.90%

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4H-Quinolizine-3-Carboxylicacid, 8-[(3S)-3-Amino-1-Pyrrolidinyl]-1-Cyclopropyl-7-Fluoro-9-Methyl-4-Oxo-,Hydrochloride (1:1) CAS NO 162763-53-3

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CAS No.:162763-53-3

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Content:99.90%

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Sitafloxacin Sesquihydrate CAS NO 163253-35-8

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CAS No.:163253-35-8

Grade:Pharmacy Grade

Content:99.90%

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3-Quinolinecarboxylic Acid, 7-[(7S)-7-Amino-5-Azaspiro[2.4]Hept-5-Yl]-8-Chloro-6-Fluoro-1-[(1R,2S)-2-Fluorocyclopropyl]-1,4-Dihydro-4-Oxo-, Hydrate (2:1) CAS NO 163253-36-9

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CAS No.:163253-36-9

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Content:99.90%

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3-Quinolinecarboxylic Acid, 7-[(7S)-7-Amino-5-Azaspiro[2.4]Hept-5-Yl]-8-Chloro-6-Fluoro-1-[(1R,2S)-2-Fluorocyclopropyl]-1,4-Dihydro-4-Oxo-, Hydrate CAS NO 163253-37-0

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CAS No.:163253-37-0

Grade:Pharmacy Grade

Content:99.90%

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3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[3-[(Ethylamino)Methyl]-1-Pyrrolidinyl]-6,8-Difluoro-1,4-Dihydro-4-Oxo- CAS NO 163554-99-2

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CAS No.:163554-99-2

Grade:Pharmacy Grade

Content:99.90%

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Pazufloxacin Mesilate CAS NO 163680-77-1

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CAS No.:163680-77-1

Grade:Pharmacy Grade

Content:99.90%

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Fandofloxacin CAS NO 164151-00-2

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CAS No.:164151-00-2

Grade:Pharmacy Grade

Content:99.90%

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