Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(3,4-Dimethylphenyl)Sulfonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the fluoroquinolone antibiotic class. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation antibacterial agents and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents.
• Antibacterial Drug Research: Used in R&D for developing new compounds targeting resistant bacterial strains.
• Chemical Synthesis: Serves as a sophisticated precursor for creating complex molecular libraries in medicinal chemistry.
• Process Development: Employed in scaling up and optimizing synthetic routes for API manufacturing under GMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) in drug design.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(3,4-Dimethylphenyl)Sulfonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1057935-02-0
Molecular Formula	C25H26FN3O5S
Molecular Weight	499.56 g/mol
Synonyms	1-Cyclopropyl-7-[4-[(3,4-dimethylphenyl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(3,4-dimethylphenylsulfonyl)piperazin-1-yl)quinoline-3-carboxylic acid; 1057935-02-0; 7-[4-[(3,4-Dimethylphenyl)sulfonyl]-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Advanced Fluoroquinolone Intermediate.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.