Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, 2,2,2-Trifluoroacetate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) derivative. This compound is critical for the research, development, and synthesis of advanced fluoroquinolone antibiotics. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on antimicrobial drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone antibiotic APIs.
• Antimicrobial Research: Used in R&D for developing new antibacterial agents targeting resistant strains.
• Process Chemistry & Scale-Up: Serves as a critical starting material or intermediate in process optimization and kilo-lab to pilot-scale production.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Biochemical Research: Used in studies investigating the mechanism of action of topoisomerase inhibitors.
• Custom Synthesis: A precursor for the custom synthesis of specialized chemical entities and molecular probes.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, 2,2,2-Trifluoroacetate
CAS No.	1215348-50-7
Molecular Formula	C20H21F4N3O4
Molecular Weight	443.40 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Trifluoroacetate; 1-Cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid 2,2,2-Trifluoroacetate; Garenoxacin Trifluoroacetate; BMS-284756 Trifluoroacetate; T-3811 Trifluoroacetate; 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Trifluoroacetate Salt
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.