Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(2-Methyl-1-Piperazinyl)-4-Oxo-, Hydrochloride is a high-purity pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of advanced fluoroquinolone antibiotics, valued for its precise chemical structure and reactivity. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis specialists for the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new antibacterial drugs.
• Chemical Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Biochemical Research: Employed in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes from laboratory to pilot and commercial production scales.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects serving the global pharmaceutical industry.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(2-Methyl-1-Piperazinyl)-4-Oxo-, Hydrochloride
CAS No.	1219097-41-2
Molecular Formula	C19H23FN3O4 • HCl
Molecular Weight	415.87 g/mol (Free base: 376.41 g/mol)
Synonyms	1-Cyclopropyl-6-fluoro-8-methoxy-7-[(2-methyl-1-piperazinyl)]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride; 7-(2-Methylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride; Garenoxacin Intermediate Hydrochloride; BMS-284756 Related Compound Hydrochloride; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(2-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid HCl; Quinolone Carboxylic Acid Derivative Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring traceability and compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.