Description

7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid, 9-Fluoro-2,3-Dihydro-3-Methyl-10-(4-Nitroso-1-Piperazinyl)-7-Oxo-, (3S)- is a high-purity, non-racemic synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound, with CAS No. 1152314-62-9, is a structurally complex molecule designed for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of next-generation therapeutics.

Application

This advanced chemical intermediate is engineered for precision synthesis in high-value applications.

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluoroquinolone antibiotic candidates and other complex heterocyclic APIs.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and optimization of API manufacturing processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying novel synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid, 9-Fluoro-2,3-Dihydro-3-Methyl-10-(4-Nitroso-1-Piperazinyl)-7-Oxo-, (3S)-
CAS No.	1152314-62-9
Molecular Formula	C₁₈H₁₈FN₅O₅
Molecular Weight	403.37 g/mol
Synonyms	(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-nitroso-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; (S)-9-Fluoro-3-methyl-10-(4-nitroso-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; 1152314-62-9; (3S)-9-Fluoro-3-methyl-10-(4-nitroso-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; A fluoroquinolone derivative intermediate; Nitroso-piperazinyl pyridobenzoxazine carboxylic acid.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a comprehensive quality management system. Every batch is characterized by advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.