Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(2-Methyl-1-Piperazinyl)-4-Oxo-, Sulfate (2:1) is a high-purity pharmaceutical intermediate of significant commercial and research importance. This compound is valued for its role as a key building block in the synthesis of advanced fluoroquinolone antibiotics. It is primarily required by pharmaceutical manufacturers and R&D organizations engaged in the development and production of next-generation antibacterial agents. Our supply is characterized by stringent quality control, ensuring batch-to-batch consistency for critical synthesis processes.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A critical intermediate in the manufacturing of novel fluoroquinolone antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial compounds with improved efficacy and safety profiles.
• Process Chemistry Optimization: Serves as a reference standard and starting material for scaling up and optimizing synthetic routes in pilot plants and commercial production.
• Analytical Standard: Employed as a high-purity standard for quality control testing, method development, and validation in analytical laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of antibiotic formulations.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(2-Methyl-1-Piperazinyl)-4-Oxo-, Sulfate (2:1)
CAS No.	1219097-42-3
Molecular Formula	C18H21FN3O4 · ½H2SO4
Molecular Weight	Contact for details
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(2-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sulfate (2:1); Garenoxacin intermediate; Garenoxacin mesylate salt intermediate; AM-1155 intermediate; BMS-284756 intermediate; T-3811 intermediate; 7-(2-Methylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid sulfate; Quinolone antibiotic intermediate.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(2-Methyl-1-Piperazinyl)-4-Oxo-, Sulfate (2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.