Description

2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde:hydrate is a high-purity, advanced steroid derivative and synthetic intermediate of significant interest in pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and reference standards. It is primarily needed by R&D chemists, process development scientists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel corticosteroid and other steroidal drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Serves as a tool compound for studying steroid hormone metabolism, receptor interactions, and enzymatic pathways in academic and industrial research settings.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex steroidal molecules.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial steroid derivatives for client-specific research programs.

Basic Information

Product Name	2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde:hydrate
CAS No.	906337-64-2
Molecular Formula	C23H30O6 • xH2O
Molecular Weight	402.48 g/mol (Anhydrous basis)
Synonyms	11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-Glyoxal Hydrate; 21-Glyoxal Cortisol Hydrate; 21-Glyoxal Hydrocortisone; (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione 21-glyoxal hydrate; 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde hydrate
EINECS	Contact for details

Quality Control

Our 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde:hydrate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (by HPLC), water content, and specific identification tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.