Description

Calcitonin, Salmon, Arg(11,18)-Lys(14)- is a synthetic analog of salmon calcitonin, a polypeptide hormone known for its potent hypocalcemic and hypophosphatemic effects. This modified peptide is engineered for enhanced stability and biological activity, making it a critical component in advanced pharmaceutical research and development. It is primarily utilized by biopharmaceutical companies and research institutions focused on metabolic bone disorders, such as osteoporosis and Paget's disease, as well as in the development of novel therapeutic formulations.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable formulations for the treatment of osteoporosis and hypercalcemia.
• Biomedical Research: Used as a reference standard and tool compound in studies of calcium metabolism, bone resorption, and receptor binding assays.
• Drug Delivery System Development: Investigated in the formulation of nasal sprays, transdermal patches, and other non-invasive delivery methods.
• Preclinical & Clinical Studies: Essential for pharmacokinetic, pharmacodynamic, and toxicology studies supporting regulatory submissions.
• Peptide Chemistry & Process Development: Serves as a model compound for optimizing solid-phase peptide synthesis (SPPS) and purification processes.
• Quality Control & Analytical Testing: Employed as a system suitability standard in HPLC and bioassay methods for product release testing.

Basic Information

Product Name	Calcitonin, Salmon, Arg(11,18)-Lys(14)-
CAS No.	116381-07-8
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₈S₂
Molecular Weight	~3431.9 g/mol
Synonyms	Salmon Calcitonin (Arg(11,18)-Lys(14) analog); [Arg11,18, Lys14]-Calcitonin (salmon); Calcitonin salmon (11,18-diamino-14-lysine); Synthetic salmon calcitonin variant; SCT-A; Hypocalcemic peptide analog; HCT; [Arg11,18,Lys14]-sCT
EINECS	Contact for details

Quality Control

Our Calcitonin, Salmon, Arg(11,18)-Lys(14)- is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and consistency, meeting the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 98.0%
Assay (Peptide Content)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetic Acid Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Biological Potency	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.