Description

Methylergonovine is a semi-synthetic ergot alkaloid derivative, recognized for its potent uterotonic activity. This high-purity pharmaceutical intermediate is critical for ensuring the efficacy and safety of final drug formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of specialized medications for obstetric and gynecological care.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of medications for postpartum hemorrhage control.
• Obstetric Therapeutics: Used in formulations to manage uterine atony and excessive bleeding following childbirth.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological studies and new drug development.
• Gynecological Applications: Employed in certain therapeutic protocols for menstrual migraine and other conditions related to vascular tone.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex ergot alkaloid derivatives.

Basic Information

Product Name	Methylergonovine
CAS No.	113-42-8
Molecular Formula	C20H25N3O2
Molecular Weight	339.44 g/mol
Synonyms	Methylergometrine; Methylergobasine; Methylergobrevin; (+)-Methylergonovine; 9,10-Didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methylergoline-8β-carboxamide; D-Lysergic acid 1-butanolamide; Methergine (brand name reference); Metilergonovina
EINECS	204-028-5

Quality Control

Our Methylergonovine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and specific identification tests, to ensure it meets exacting standards suitable for pharmaceutical use. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.