Description

17Alpha-Hydroxy-16Beta-Methylpregnenolone is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound matters for its role as a key building block in the production of more complex, biologically active steroid molecules. Pharmaceutical R&D and manufacturing teams need it for the development and scalable production of advanced therapeutic agents, particularly within the steroid hormone class.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent corticosteroid and other steroid-based active pharmaceutical ingredients (APIs).
• Steroid Hormone Research: Serves as a valuable reference standard and starting material in academic and industrial research exploring new steroid derivatives and their biological activities.
• Process Development: Used by process chemists to develop and optimize efficient, cost-effective synthetic routes for complex steroid molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) engaged in the production of steroid-based drugs under cGMP conditions.

Basic Information

Product Name	17Alpha-Hydroxy-16Beta-Methylpregnenolone
CAS No.	13900-61-3
Molecular Formula	C22H34O3
Molecular Weight	346.51 g/mol
Synonyms	16β-Methyl-17α-hydroxypregnenolone; (3β)-3-Hydroxy-16β-methylpregn-5-en-20-one; 17α-Hydroxy-16β-methylpregn-5-en-3β-ol-20-one; 16β-Methyl-17α-hydroxypregn-5-en-3β-ol-20-one; Pregnenolone, 17-hydroxy-16-methyl-; 16β-Methyl-17α-hydroxy-δ5-pregnenolone
EINECS	Contact for details

Quality Control

Our 17Alpha-Hydroxy-16Beta-Methylpregnenolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.