Description

(R)-CBHA-DMDA, also known as (1R,2R)-N,Nμ-Dihydroxy-N,Nμ-bis(3,5-dimethyldiphenylacetyl)-cyclohexane-diamine, is a high-purity, chiral dihydroxamic acid derivative that serves as a sophisticated chelating agent and chiral auxiliary. Its precise stereochemistry and functional groups make it a valuable building block for the development of asymmetric catalysts and selective metal ion scavengers in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantioselective control and high-affinity metal coordination for complex molecule development.

Application

• Asymmetric Catalysis: As a chiral ligand or auxiliary in transition metal-catalyzed reactions, such as asymmetric hydrogenation, epoxidation, and C-H activation.
• Pharmaceutical Intermediate: Synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex drug candidates.
• Metal Chelation & Separation: Selective extraction and purification of specific metal ions in analytical chemistry and hydrometallurgy.
• Agrochemical Research: Development of novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Precursor for functionalized polymers and metal-organic frameworks (MOFs) with chiral recognition properties.
• Analytical Reagent: Use as a chiral selector or derivatizing agent in chromatography (HPLC, GC) for enantiomeric separation and analysis.

Basic Information

Product Name	(R)-CBHA-DMDA
CAS No.	860036-27-7
Molecular Formula	C48H52N2O4
Molecular Weight	720.94 g/mol
Synonyms	(1R,2R)-N,N'-Dihydroxy-N,N'-bis(3,5-dimethyldiphenylacetyl)-cyclohexane-diamine; N,N'-(1R,2R)-1,2-Cyclohexanediylbis[α-(3,5-dimethylphenyl)-N-hydroxy-3,5-dimethyl-benzeneacetamide]; (R,R)-CBHA-DMDA; (1R,2R)-Cyclohexane-1,2-diylbis[N-hydroxy-2-(3,5-dimethylphenyl)-3,5-dimethylbenzamide]; Chiral Dihydroxamic Acid Derivative; (R,R)-N,N'-Bis(3,5-dimethylbenzoyl)-N,N'-dihydroxy-1,2-cyclohexanediamine
EINECS	Contact for details

Quality Control

Our (R)-CBHA-DMDA is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.