Description

Sepimostat is a potent and selective serine protease inhibitor, specifically targeting enzymes like trypsin and thrombin. This compound is crucial for research and development in the pharmaceutical and life sciences sectors, where precise enzyme modulation is required. It is primarily utilized by researchers and manufacturers in the fields of inflammation research, thrombosis studies, and drug discovery for novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying serine protease pathways involved in inflammation and coagulation.
• Inflammation Studies: Investigation of trypsin-like proteases in inflammatory diseases and potential therapeutic interventions.
• Thrombosis Research: Exploration of thrombin inhibition mechanisms for developing anti-thrombotic agents.
• Biochemical Assay Development: Used as a reference standard or active component in enzymatic assays and diagnostic kit development.
• Academic Research: Fundamental research in biochemistry, enzymology, and cell signaling pathways.
• Pre-clinical Studies: Evaluation of efficacy and mechanism of action in animal models for relevant disease states.

Basic Information

Product Name	Sepimostat
CAS No.	103926-64-3
Molecular Formula	C20H21N5O4S
Molecular Weight	427.48 g/mol
Synonyms	Sepimostat; FUTHAN; Nafamostat impurity; (2S,3aS,7aS)-1-[(2S)-2-Carbamoyl-1-pyrrolidinyl]-2-[(4-guanidinobenzoyl)oxy]-2,3,3a,4,5,6,7,7a-octahydro-1H-indole-7-carboxylic acid; Futhan (Sepimostat); GU-106; GU106; MDL 101043
EINECS	Contact for details

Quality Control

Our Sepimostat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.