Description

Sepimostate Mesilate is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in advanced pharmaceutical research and development. This compound is critical for studying viral replication mechanisms and developing next-generation antiviral therapies. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on virology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antiviral active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in virology studies, particularly for investigating HIV-1 reverse transcriptase inhibition.
• Preclinical Development: Employed in in vitro and in vivo studies to assess pharmacokinetics, efficacy, and safety profiles of new drug candidates.
• Process Chemistry: Acts as a critical intermediate in scale-up and optimization of manufacturing routes for antiviral drugs.
• Quality Control & Analytical Standards: Provides a certified reference material for method development and validation in analytical laboratories.

Basic Information

Product Name	Sepimostate Mesilate
CAS No.	103926-82-5
Molecular Formula	C15H18N6O2S • CH4O3S
Molecular Weight	438.48 g/mol
Synonyms	Sepimostat Mesylate; TPCN; TPCN (Mesylate); TPCN Mesylate; 5-[(3-Aminophenyl)methyl]-N,N-dimethyl-2,4-pyrimidinediamine monomethanesulfonate; Sepimostat Methanesulfonate; TPCN Mesilate; (5-((3-Aminobenzyl)amino)-N,N-dimethylpyrimidine-2,4-diamine methanesulfonate)
EINECS	Contact for details

Quality Control

Our Sepimostate Mesilate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.