Description

(3S,5S,7S,13E,16S,17E,19R,21E)-5-Ethyl-7,19-dihydroxy-3-[(R)-1-(1H-indol-3-yl)ethyl]-16,18-dimethyl-10,11-dinor[13]cytochalasa-6(12),13,17,21-tetrene-1,20,23-trione is a complex cytochalasan derivative, a class of fungal metabolites known for their potent biological activity. This compound is of significant interest for advanced research in cell biology and pharmacology due to its unique structural features and potential as a biochemical tool. It is primarily utilized by research institutions and pharmaceutical development laboratories investigating cytoskeletal dynamics, cellular transport, and novel therapeutic pathways.

Application

• Biochemical Research: As a high-purity reference standard for studying cytochalasin mechanisms of action.
• Pharmaceutical R&D: Serving as a key intermediate or lead compound in the discovery of new bioactive molecules targeting cellular processes.
• Cell Biology Studies: Used as a research-grade reagent to investigate actin polymerization inhibition and its effects on cell motility and morphology.
• Academic Research: Employed in university and institutional labs for fundamental studies in natural product chemistry and mycotoxin research.
• Standards and Metrology: For use in analytical method development and validation within quality control laboratories.

Basic Information

Product Name	(3S,5S,7S,13E,16S,17E,19R,21E)-5-Ethyl-7,19-dihydroxy-3-[(R)-1-(1H-indol-3-yl)ethyl]-16,18-dimethyl-10,11-dinor[13]cytochalasa-6(12),13,17,21-tetrene-1,20,23-trione
CAS No.	83481-23-6
Molecular Formula	C₃₄H₄₁NO₇
Molecular Weight	575.70 g/mol
Synonyms	Cytochalasin Z8; 19-Deoxycytochalasin D; 19-Deoxycytochalasin D (Z8); Cytochalasin Z₈; [13]Cytochalasin-6(12),13,17,21-tetraene-1,20,23-trione, 5-ethyl-7,19-dihydroxy-3-[(1R)-1-(1H-indol-3-yl)ethyl]-16,18-dimethyl-10,11-dinor-, (3S,5S,7S,13E,16S,17E,19R,21E)-; 83481-23-6; 19-Desoxycytochalasin D
EINECS	Contact for details

Quality Control

Our (3S,5S,7S,13E,16S,17E,19R,21E)-5-Ethyl-7,19-dihydroxy-3-[(R)-1-(1H-indol-3-yl)ethyl]-16,18-dimethyl-10,11-dinor[13]cytochalasa-6(12),13,17,21-tetrene-1,20,23-trione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.