Description

Antimycin A is a potent secondary metabolite and a well-characterized inhibitor of mitochondrial electron transport. This compound is critical for researchers and industries requiring precise biochemical tools to study cellular respiration, apoptosis, and energy metabolism. It serves as an essential reagent for life science research, agricultural studies, and as a reference standard in analytical laboratories.

Application

• Biochemical Research: Widely used as a specific inhibitor of the mitochondrial electron transport chain (Complex III) to study oxidative phosphorylation, ATP production, and reactive oxygen species (ROS) generation.
• Apoptosis Studies: Employed to induce programmed cell death in various cell lines for cancer research and mechanistic studies of cell survival pathways.
• Agricultural Research: Investigated for its insecticidal and fungicidal properties, serving as a model compound in the development of novel crop protection agents.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation in pharmaceutical and academic settings.
• Metabolic Pathway Analysis: A key tool in metabolic flux analysis and bioenergetics to understand the impact of mitochondrial dysfunction in disease models.
• Antibiotic Research: Studied for its mechanism of action as a natural antibiotic, contributing to the understanding of bacterial and fungal respiration.

Basic Information

Product Name	Antimycin A
CAS No.	1397-94-0
Molecular Formula	C28H40N2O9
Molecular Weight	548.63 g/mol
Synonyms	Antimycin A1; Antipiricullin; Blastmycin; Virosin; NSC 13519; UNII-5Q4K8R8UHL; 3-[(2R,3S,6S,7R,8R)-3-[(2S,3S)-3-(Formamido)-2-hydroxybutanoyl]oxy-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]amino-3-oxopropyl 3-methylbutanoate
EINECS	215-754-8

Quality Control

Our Antimycin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. The product is hygroscopic and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.