Description

5-(n-Butyl-n-Methyl)Amiloride is a high-purity, research-grade chemical compound, a derivative of the classic sodium channel blocker amiloride. This compound is valued for its specific inhibitory activity and is a critical tool in biochemical and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers focused on ion channel studies and drug discovery.

Application

• Biochemical Research: Used as a selective inhibitor in studies of epithelial sodium channels (ENaC) and other ion transport mechanisms.
• Pharmacological Studies: Serves as a reference standard and active compound in preclinical research for cardiovascular and renal function.
• Pharmaceutical Development: Employed as a key intermediate or reference molecule in the synthesis and testing of novel therapeutic agents.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cell biology and physiology.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of specialized diagnostic kits for research purposes.

Basic Information

Product Name	5-(n-Butyl-n-Methyl)Amiloride
CAS No.	1154-79-6
Molecular Formula	C12H19Cl2N7O
Molecular Weight	348.23 g/mol
Synonyms	5-(N-Butyl-N-methyl)amiloride; 5-(N-Butyl-N-methylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide; Benzamil analog; BMA; 5-(Butylmethylamino)-6-chloro-N-(diaminomethylidene)-3-pyrazinecarboxamide; Amiloride 5-N-butyl-N-methyl analog; 5-(N-Butyl-N-methyl)amiloride hydrochloride (if applicable)
EINECS	Contact for details

Quality Control

Our 5-(n-Butyl-n-Methyl)Amiloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.