Description

Quinacrine Mustard Dihydrochloride is a chemically modified derivative of the classic antimalarial agent quinacrine, designed for research applications. This compound is valued for its ability to act as a bifunctional alkylating agent and a fluorescent probe, enabling specific covalent labeling and detection of biomolecules. It is primarily utilized by researchers and scientists in the fields of molecular biology, cytogenetics, and biochemistry for chromosome banding studies, nucleic acid staining, and protein interaction analysis.

Application

• Chromosome Banding (Q-banding): A primary application for the fluorescent staining of chromosomes to produce characteristic banding patterns for karyotype analysis and cytogenetic studies.
• Nucleic Acid Staining: Used as a fluorescent stain for DNA and RNA in gel electrophoresis, in situ hybridization, and other molecular biology techniques.
• Biomolecular Labeling: Acts as a covalent labeling reagent for proteins and nucleic acids due to its mustard group, facilitating tracking and interaction studies.
• Research Reagent: Serves as a key biochemical tool in academic and pharmaceutical research for investigating cellular processes, mutagenesis, and DNA-protein crosslinking.
• Fluorescence Microscopy: Employed as a specific fluorescent tag in cell imaging to visualize chromosomal structures and other subcellular components.
• Diagnostic Development: Potential use in the development of research-grade diagnostic assays and kits for genetic analysis.

Basic Information

Product Name	Quinacrine Mustard Dihydrochloride
CAS No.	4213-45-0
Molecular Formula	C23H30Cl3N3O • 2HCl
Molecular Weight	543.3 g/mol (for free base C23H30Cl3N3O)
Synonyms	Quinacrine Mustard 2HCl; ICR-100; NSC-113019; 6-Chloro-9-[[4-(bis(2-chloroethyl)amino)-1-methylbutyl]amino]-2-methoxyacridine Dihydrochloride; 2-Methoxy-6-chloro-9-[(1-methyl-4-di(2-chloroethyl)aminobutyl)amino]acridine Dihydrochloride; Quinacrine Mustard Hydrochloride; QM Dihydrochloride
EINECS	Contact for details

Quality Control

Our Quinacrine Mustard Dihydrochloride is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.