Description

Dihexa is a potent, orally active small molecule peptide mimetic known for its high affinity to hepatocyte growth factor (HGF) and its receptor, c-Met. This compound is of significant interest in research and development for its neurotrophic and cognitive-enhancing properties. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories focused on neuroscience, cognitive disorders, and regenerative medicine.

Application

• Neuroscience Research: Investigated for its potential to promote synaptogenesis and neurogenesis in models of neurodegenerative diseases.
• Cognitive Function Studies: Used in preclinical research to study mechanisms of learning, memory enhancement, and cognitive recovery.
• Neuroprotection: Explored for its ability to protect neuronal cells from damage and apoptosis in various experimental settings.
• Pharmaceutical Intermediate: Serves as a key intermediate in the synthesis of advanced therapeutic candidates targeting the HGF/c-Met pathway.
• Biochemical Tool Compound: Employed in vitro and in vivo to study the signaling pathways and biological functions associated with c-Met receptor activation.

Basic Information

Product Name	Dihexa
CAS No.	1401708-83-5
Molecular Formula	C₃₃H₄₄N₆O₆
Molecular Weight	608.74 g/mol
Synonyms	N-hexanoic-Tyr-Ile-(6) aminohexanoic amide; Dihexa peptide; 4-[[(2S)-2-[[(2S)-2-[[6-aminohexanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]butanoic acid; PNB-0408; MM-201
EINECS	Contact for details

Quality Control

Our Dihexa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.