Description

(1S,5R,8S)-7-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethyl-butanoyl]-N-[1-(cyclopropylcarbamoyl)-1-oxo-pentan-2-yl]-7-azabicyclo[3.3.0]octane-8-carboxamide is a sophisticated, high-purity organic compound with a complex bicyclic structure, serving as a critical building block in advanced pharmaceutical research and development. Its precise stereochemistry and functional groups make it an invaluable intermediate for synthesizing novel therapeutic agents, particularly in targeted drug discovery programs. This compound is essential for research chemists and process development scientists in the pharmaceutical and biotechnology industries working on next-generation treatments.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in protease inhibitor research.
• Drug Discovery & Medicinal Chemistry: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the optimization and pilot-scale production of complex drug molecules.
• Biochemical Research: Employed as a tool compound or a precursor in studying enzyme-substrate interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering specialized synthesis services.

Basic Information

Product Name	(1S,5R,8S)-7-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethyl-butanoyl]-N-[1-(cyclopropylcarbamoyl)-1-oxo-pentan-2-yl]-7-azabicyclo[3.3.0]octane-8-carboxamide
CAS No.	569364-34-7
Molecular Formula	C₃₈H₅₄N₈O₇
Molecular Weight	734.89 g/mol
Synonyms	7-Azabicyclo[3.3.0]octane-8-carboxamide derivative; Bicyclic Peptidomimetic Intermediate; CAS 569364-34-7; (1S,5R,8S)-Isomer of complex azabicyclooctane carboxamide; N-[(1S)-1-(Cyclopropylcarbamoyl)pentyl]-7-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-7-azabicyclo[3.3.0]octane-8-carboxamide
EINECS	Contact for details

Quality Control

Our (1S,5R,8S)-7-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethyl-butanoyl]-N-[1-(cyclopropylcarbamoyl)-1-oxo-pentan-2-yl]-7-azabicyclo[3.3.0]octane-8-carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.