Description

(2S)-2-Methyl-2-oxiranecarboxylic acid [(1aR,3S,4E,7S,10aS,10bR)-3-acetoxy-8-acetoxymethyl-1a,2,3,6,7,9,10a,10b-octahydro-1a,5-dimethyl-9-oxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl] ester is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its intricate stereochemistry and functional groups, which make it a critical building block for the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and anti-infective fields.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Synthetic Organic Chemistry: Serves as a valuable substrate for developing novel synthetic methodologies, including stereoselective transformations.
• Bioconjugation & Prodrug Development: Potential utility in designing targeted drug delivery systems or prodrugs due to its reactive ester and epoxide functionalities.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-Methyl-2-oxiranecarboxylic acid [(1aR,3S,4E,7S,10aS,10bR)-3-acetoxy-8-acetoxymethyl-1a,2,3,6,7,9,10a,10b-octahydro-1a,5-dimethyl-9-oxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl] ester
CAS No.	52229-58-0
Molecular Formula	C24H30O10
Molecular Weight	478.49 g/mol
Synonyms	2-Methyloxirane-2-carboxylic acid (1aR,3S,4E,7S,10aS,10bR)-3-acetoxy-8-acetoxymethyl-1a,2,3,6,7,9,10a,10b-octahydro-1a,5-dimethyl-9-oxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl ester; 2-Methylglycidic acid ester derivative of a cyclodecafuran; (S)-2-Methylglycidic acid, ester with a complex furanoterpenoid alcohol; Contact for additional systematic names.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity essential for sensitive pharmaceutical applications. All material is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.