Description

n-Formyldemecolcine is a chemically modified derivative of the natural alkaloid demecolcine, characterized by the introduction of a formyl group. This modification is of significant interest in pharmaceutical research and development, particularly for creating novel compounds with targeted biological activity. It serves as a crucial advanced pharmaceutical intermediate for researchers and manufacturers in the life sciences sector. Key industries that utilize this specialized compound include pharmaceutical R&D, biotechnology, and academic research institutions focused on oncology and cytological studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents and experimental drugs.
• Biochemical Research: Used as a reference standard or active component in studies investigating microtubule dynamics and cell cycle inhibition.
• Anticancer Agent Development: Acts as a precursor or model compound in the research and development of new chemotherapeutic candidates.
• Life Science Reagent: Employed in specialized laboratory settings for cytological and molecular biology applications.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for fundamental and applied research projects.

Basic Information

Product Name	n-Formyldemecolcine
CAS No.	14686-61-4
Molecular Formula	C22H26N2O5
Molecular Weight	398.46 g/mol
Synonyms	N-Formyl-N-desacetyl-N-methylcolchicine; N-Formyldemecolcine; N-Formyl-N-deacetyl-N-methylcolchicine; Deacetyl-N-methylcolchicine N-formyl; Colchicine, N-deacetyl-N-methyl-, N-formyl-; Demecolcine, N-formyl-; N-Formyl-N-deacetylmethylcolchicine
EINECS	Contact for details

Quality Control

Our n-Formyldemecolcine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which are available upon request. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.