Description

1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester is a sophisticated, high-purity synthetic intermediate designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists exploring novel therapeutic pathways, particularly in kinase inhibition and targeted oncology. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers requiring precise, high-quality building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly for kinase-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for oncology and other therapeutic areas.
• Biochemical Assay Development: Serves as a reference standard or probe compound in enzymatic and cellular screening assays.
• Preclinical Development: Utilized in the production of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester
CAS No.	2326428-25-3
Molecular Formula	C27H39N7O4
Molecular Weight	525.65 g/mol
Synonyms	4-((5-Methyl-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl)amino)-1-((2E)-4-(dimethylamino)-1-oxobut-2-en-1-yl)piperidine-1-carboxylic acid 3-pyrrolidinyl ester; (2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl 3-pyrrolidinyl 4-[(5-methyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)amino]piperidine-1-carboxylate; 1-[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-1-piperidinecarboxylate; 3-Pyrrolidinol, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-1-piperidinecarboxylate (ester); CAS 2326428-25-3
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.