Description

(NZ)-N-[(2S)-2-[(3Z,8S,9S,10R,13R,14S,17R)-3-hydroxyimino-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propylidene]hydroxylamine is a high-purity, steroidal oxime derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate for synthesizing novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Biochemical Research: Used as a reference standard or probe in studies of steroid hormone action, metabolism, and receptor binding assays.
• Drug Discovery & Development: Serves as a precursor in medicinal chemistry programs for creating libraries of compounds with potential anti-cancer or anti-inflammatory activity.
• Academic Research: Employed in university and institutional labs for investigating the structure-activity relationships (SAR) of modified steroidal frameworks.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(NZ)-N-[(2S)-2-[(3Z,8S,9S,10R,13R,14S,17R)-3-hydroxyimino-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propylidene]hydroxylamine
CAS No.	28444-84-0
Molecular Formula	C24H38N2O2
Molecular Weight	386.57 g/mol
Synonyms	17β-[(1Z)-1-(Hydroxyimino)propyl]-3-oximinoandrostane; 3,17-Dioximinopregnane derivative; Steroidal dioxime; Androstane-3,17-dione dioxime; (3Z,17Z)-Pregna-3,17-dione dioxime; 3,17-Bis(hydroxyimino)androstane; Contact for additional trade names and systematic IUPAC variants.
EINECS	Contact for details

Quality Control

Our (NZ)-N-[(2S)-2-[(3Z,8S,9S,10R,13R,14S,17R)-3-hydroxyimino-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propylidene]hydroxylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.