Description

Anion Standard - Malate CAS NO 149-61-1 is a high-purity analytical reference material of malic acid anion, a critical dicarboxylic acid intermediate in biological and industrial processes. This standard is essential for ensuring the accuracy and reliability of quantitative analyses in quality control and research laboratories. It is primarily used by professionals in the pharmaceutical, food & beverage, and biotechnology sectors for method development, validation, and routine calibration of instruments like ion chromatography (IC) and high-performance liquid chromatography (HPLC).

Application

• Analytical Reference Standard: Primary use for calibrating ion chromatography (IC) and HPLC systems in the quantitative analysis of malate and related anions.
• Pharmaceutical Quality Control: Used in the assay and impurity profiling of drug substances and excipients where malate is a counterion or degradation product.
• Food & Beverage Analysis: Essential for testing malic acid content in wines, fruit juices, candies, and other food products to verify authenticity and compliance with labeling.
• Biochemical Research: Serves as a standard in metabolic studies, particularly in the citric acid (Krebs) cycle and plant physiology research.
• Method Development & Validation: A critical tool for developing, optimizing, and validating new analytical methods in compliance with ICH, USP, or EP guidelines.
• Environmental Testing: Can be used in the analysis of organic acids in water and soil samples.

Basic Information

Product Name	Anion Standard - Malate
CAS No.	149-61-1
Molecular Formula	C4H4O52- (as anion)
Molecular Weight	132.07 g/mol (for acid form, C4H6O5)
Synonyms	Malate Standard; Malic Acid Anion Standard; Hydroxysuccinic Acid Anion; L-Malate (typically); DL-Malate; Apple Acid Anion; 2-Hydroxybutanedioate; Food Additive E296 (anion form).
EINECS	205-737-3 (for malic acid)

Quality Control

Our Anion Standard - Malate is manufactured under strict quality management systems. Each batch is rigorously tested to ensure high purity, accurate concentration, and traceability. Certificates of Analysis (COA) are provided, detailing the results for assay, identity, and purity by techniques such as ion chromatography and titration. The product is suitable for use in environments requiring compliance with GMP, ISO 17025, and ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). The standard solution should be kept in its original container to maintain stability and prevent contamination. For long-term storage of prepared dilutions, follow the specific recommendations provided in the accompanying technical data sheet.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless liquid
Identification (IC/HPLC)	Conforms to reference standard
Assay (Titration)	98.0 - 102.0% of stated concentration
Concentration	Typically 1000 mg/L (or as specified)
Matrix	Aqueous or specified solvent
pH	As specified per grade
Related Anions (IC)	Meets grade-specific purity requirements
Trace Metals (ICP-MS)	< 1 ppm total (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.