Description

Dansyl-L-Phenylalanine is a high-purity, fluorescently labeled derivative of the essential amino acid L-phenylalanine. This compound is a critical reagent in advanced biochemical research and analytical method development, valued for its strong fluorescence and specific molecular recognition properties. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for applications requiring sensitive detection and quantification.

Application

• Fluorescent Labeling Agent: Used as a derivatization reagent in High-Performance Liquid Chromatography (HPLC) and capillary electrophoresis for the sensitive detection and quantification of amino acids, peptides, and amines.
• Biochemical Research: Serves as a substrate or probe in enzyme activity assays (e.g., for proteases and peptidases) and in studies of protein structure, function, and interactions.
• Pharmaceutical Analysis: Employed in the development and validation of analytical methods for drug purity testing, impurity profiling, and stability studies of peptide-based pharmaceuticals.
• Diagnostic Reagent Manufacturing: Acts as a key component in the synthesis of fluorescent tags and conjugates for in-vitro diagnostic kits and biomedical imaging agents.
• Proteomics and Metabolomics: Utilized in mass spectrometry and fluorescence-based workflows for the identification and characterization of biomolecules in complex biological samples.

Basic Information

Product Name	Dansyl-L-Phenylalanine
CAS No.	1104-36-5
Molecular Formula	C21H20N2O4S
Molecular Weight	396.46 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-L-phenylalanine; DNS-Phe; Dansylphenylalanine; L-Phenylalanine, N-[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-; N-Dansyl-L-phenylalanine; 1-Dimethylaminonaphthalene-5-sulfonyl-L-phenylalanine; Dns-Phe-OH
EINECS	214-170-5

Quality Control

Our Dansyl-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.