Description

Nicotine Ditartrate Dihydrate is a stable, crystalline salt form of nicotine, widely used as a key reference standard and active ingredient. This compound is essential for ensuring accurate quantification and quality control in analytical and manufacturing processes. It is primarily utilized by the pharmaceutical, research, and agrochemical industries for applications requiring precise nicotine content.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and validation of methods in drug testing and quality control laboratories.
• Active Pharmaceutical Ingredient (API): Serves as a controlled-release component in nicotine replacement therapies (NRTs) such as gums, lozenges, and transdermal patches.
• Biochemical Research: Employed in neuroscience and pharmacology studies as a selective agonist for nicotinic acetylcholine receptors (nAChRs).
• Agrochemical Formulations: Used in the development of specific insecticides and behavioral modifiers due to its potent neuroactive properties.
• Veterinary Medicine: Applied in certain ectoparasiticide products for animal health.
• Chemical Synthesis: Acts as a stable precursor or intermediate in the synthesis of more complex nicotine derivatives and analogs.

Basic Information

Product Name	Nicotine Ditartrate Dihydrate
CAS No.	6019-06-3
Molecular Formula	C10H14N2·2C4H6O6·2H2O
Molecular Weight	498.45 g/mol
Synonyms	Nicotine Bitartrate Dihydrate; (-)-Nicotine Ditartrate Dihydrate; (S)-Nicotine Hydrogen Tartrate Dihydrate; L-Nicotine Ditartrate Salt Dihydrate; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate dihydrate; Nicotine Tartrate; Nicotine Acid Tartrate Dihydrate
EINECS	Contact for details

Quality Control

Our Nicotine Ditartrate Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	6.0% - 8.0%
Specific Rotation	-78° to -82° (c=2 in H2O)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.