Description

(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(8S,9S,13S,14S)-2-methoxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-2-carboxylic acid is a high-purity, structurally defined steroidal glycosidic acid of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical characterization of complex bioactive molecules. It is essential for R&D teams in the pharmaceutical, biotechnology, and fine chemical sectors focused on steroid chemistry, drug discovery, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and hormone analogs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of related steroid compounds.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor binding assays, and metabolic pathway investigations.
• Academic & Discovery Chemistry: A valuable reagent for synthesizing complex molecular libraries and exploring new chemical entities in medicinal chemistry programs.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialized, high-value chemical products.

Basic Information

Product Name	(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(8S,9S,13S,14S)-2-methoxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-2-carboxylic acid
CAS No.	25577-70-2
Molecular Formula	C26H36O10
Molecular Weight	508.56 g/mol
Synonyms	Estrone 3-Glucuronide; Estrone 3-β-D-Glucuronide; E1-3G; 3-Hydroxyestra-1,3,5(10)-trien-17-one 3-glucuronide; Estrone glucuronide; 17-Oxoestra-1,3,5(10)-trien-3-yl β-D-Glucopyranosiduronic Acid
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict in-process controls and is validated by comprehensive analytical testing. Each batch is characterized using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤3.0%
Residue on Ignition	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0%
Single Maximum Impurity	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.