Description

[1S-[1α,2α,4α(4R*,5S*),7β,8aS*,9aα,10aα,12aα,12bα]]-2,2-DiMethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[7,12a-Bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-triMethyl-8-oxo-2,6-Methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl] 3-(1,1-diMethylethyl) Ester is a highly complex, multi-functional organic compound belonging to the taxane diterpenoid class. This compound matters as a sophisticated chemical intermediate or reference standard in advanced pharmaceutical research and development. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing novel oncology therapeutics and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs), particularly in the taxane family.
• Oncology Drug Research: Serves as a critical precursor or analog in the research and development of next-generation chemotherapeutic agents.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling of related pharmaceutical compounds.
• Process Chemistry Development: Employed in route scouting and optimization studies for the efficient and scalable production of complex molecular architectures.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic benefits.
• Academic & Institutional Research: Supports cutting-edge chemical and biochemical research in universities and government institutions focusing on natural product synthesis and bioactivity.

Basic Information

Product Name	[1S-[1α,2α,4α(4R*,5S*),7β,8aS*,9aα,10aα,12aα,12bα]]-2,2-DiMethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[7,12a-Bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-triMethyl-8-oxo-2,6-Methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl] 3-(1,1-diMethylethyl) Ester
CAS No.	168120-68-1
Molecular Formula	C52H59NO14
Molecular Weight	922.03 g/mol
Synonyms	Taxol C-13 Side Chain N-t-BOC Derivative; 10-Deacetylbaccatin III 7,13-O-Diacetyl-10-O-benzoyl-2-O-[(2R,3S)-3-(tert-Butoxycarbonylamino)-2-hydroxy-3-phenylpropionyl]; 7,13-Diacetyl-10-benzoyl-2-[(2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionyl]oxy-10-deacetylbaccatin III; Baccatin III, 7,13-bis(acetyloxy)-10-(benzoyloxy)-2-[[(2R,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-3-phenyl-1-oxopropoxy]methyl]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; Paclitaxel Side Chain N-BOC Protected; tert-Butyl (2R,3S)-3-[[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Bis(acetyloxy)-15-[(benzoyloxy)methyl]-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl]oxy]-2-hydroxy-3-phenylpropyl]carbamate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled and stored under anhydrous conditions in a dry environment. Keep container tightly sealed in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.