Description

(2S)-N-[(2S,5S)-3,3-difluoro-5-[[(2S)-3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanoyl]amino]-4-oxo-1,6-diphenyl-hexan-2-yl] -3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanamide is a sophisticated, high-purity synthetic peptide derivative designed for advanced research and development. This compound is critical for pharmaceutical and biochemical research, particularly in the study of enzyme inhibition and targeted therapeutic pathways. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and academic sectors for developing novel active pharmaceutical ingredients (APIs) and probes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide-based drug candidates.
• Protease Inhibitor Research: Used as a reference standard or active component in biochemical assays targeting specific protease enzymes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Bioconjugation: Acts as a specialized linker or payload in the development of antibody-drug conjugates (ADCs) and other targeted therapies.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and peptide science.
• Process Development: Supports scale-up and optimization of synthetic routes for GMP manufacturing of clinical trial materials.

Basic Information

Product Name	(2S)-N-[(2S,5S)-3,3-difluoro-5-[[(2S)-3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanoyl]amino]-4-oxo-1,6-diphenyl-hexan-2-yl] -3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanamide
CAS No.	144162-29-8
Molecular Formula	C52H62F2N8O6
Molecular Weight	933.11 g/mol
Synonyms	Boc-D-Phe-Phe-NH-CH2-COOH; (2S)-N-[(2S,5S)-3,3-difluoro-5-[[(2S)-3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanoyl]amino]-4-oxo-1,6-diphenylhexan-2-yl]-3-methyl-2-[(methyl(pyridin-2-ylmethyl)carbamoyl)amino]butanamide; Difluorinated Peptidomimetic Inhibitor; Peptide-based Protease Inhibitor Analog; Custom Fluorinated Peptide
EINECS	Contact for details

Quality Control

Our (2S)-N-[(2S,5S)-3,3-difluoro-5-[[(2S)-3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanoyl]amino]-4-oxo-1,6-diphenyl-hexan-2-yl] -3-methyl-2-[(methyl-(pyridin-2-ylmethyl)carbamoyl)amino]butanamide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.