Description

5,6,7,8,9,10,15a,16,17,17a,17b,18,18a,19a,19b,20,20a,20b-Octadecahydro-8,11-dihydroxy-18-methyl-9,12-methano-1H-oxireno[4,5]pentaleno[1,2-s]-5,10-benzodiazacycloheptadecine-4,13,21-trione is a complex, high-purity macrocyclic compound of significant interest in advanced pharmaceutical research and development. Its intricate polycyclic structure makes it a valuable intermediate or reference standard for the synthesis of novel active pharmaceutical ingredients (APIs) and for biochemical studies. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel, complex drug candidates, especially in oncology and anti-infective research.
• Biochemical Research: Used as a reference standard or probe in studying enzyme inhibition, receptor binding, and other molecular interaction mechanisms due to its specific structural features.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic synthesis and for investigating structure-activity relationships (SAR).
• Process Development & Scale-up: Utilized by process chemists to develop and optimize scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	5,6,7,8,9,10,15a,16,17,17a,17b,18,18a,19a,19b,20,20a,20b-Octadecahydro-8,11-dihydroxy-18-methyl-9,12-methano-1H-oxireno[4,5]pentaleno[1,2-s]-5,10-benzodiazacycloheptadecine-4,13,21-trione
CAS No.	134458-00-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complex Macrocyclic Diketone; Oxireno-pentaleno-benzodiazacycloheptadecine derivative; CAS 134458-00-7; 18-Methyl-8,11-dihydroxy-9,12-methano-oxireno[4,5]pentaleno[1,2-s]benzodiazacycloheptadecine-trione; Research Compound 134458-00-7; Advanced Pharmaceutical Intermediate 134458-00-7; Polycyclic Lactam Intermediate
EINECS	Contact for details

Quality Control

Our 5,6,7,8,9,10,15a,16,17,17a,17b,18,18a,19a,19b,20,20a,20b-Octadecahydro-8,11-dihydroxy-18-methyl-9,12-methano-1H-oxireno[4,5]pentaleno[1,2-s]-5,10-benzodiazacycloheptadecine-4,13,21-trione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and MS. Our quality commitment aligns with the standards expected for pharmaceutical R&D and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.