Description

(2S)-1-[(10R,13S,16S,19S,22R)-19-benzyl-13-(carbamoylmethyl)-22-[(4-ethoxyphenyl)methyl]-12,15,18,21,24-pentaoxo-16-propan-2-yl-3,7,8-trithia-11,14,17,20,23-pentazaspiro[5.19]pentacosane-10-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)-4-(diaminomethylideneamino)butyl]pyrrolidine-2-carboxamide is a complex, high-purity synthetic peptide derivative designed for advanced research and development. This compound is of significant interest for its potential role as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents. It is primarily targeted at pharmaceutical R&D laboratories and biotechnology companies engaged in drug discovery programs, particularly those focusing on peptide-based therapeutics.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of novel peptide-based drug candidates.
• Drug Discovery Programs: Used in high-throughput screening and biological activity assays to identify potential therapeutic leads.
• Bioconjugation & Probe Development: Acts as a scaffold for creating labeled probes for diagnostic imaging or targeted drug delivery studies.
• Chemical Biology Studies: Employed to investigate protein-protein interactions, enzyme inhibition, or cellular signaling pathways.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for Good Manufacturing Practice (GMP) production.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	(2S)-1-[(10R,13S,16S,19S,22R)-19-benzyl-13-(carbamoylmethyl)-22-[(4-ethoxyphenyl)methyl]-12,15,18,21,24-pentaoxo-16-propan-2-yl-3,7,8-trithia-11,14,17,20,23-pentazaspiro[5.19]pentacosane-10-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)-4-(diaminomethylideneamino)butyl]pyrrolidine-2-carboxamide
CAS No.	133073-76-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Peptide Spirocycle Derivative; Complex Peptide Thioether; Benzyl-Carbamoylmethyl Spirocycle; 4-Ethoxybenzyl Peptide Intermediate; Pentazaspiro[5.19]pentacosane Derivative; CAS 133073-76-4; Research Peptide 133073-76-4
EINECS	Contact for details

Quality Control

Our production of this advanced peptide intermediate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from advanced techniques such as HPLC, LC-MS, and NMR. We support our clients with the documentation necessary for regulatory filings and internal quality audits.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.