Description

(3R,4S,7S)-7β-[(1H-Indol-3-yl)methyl]-3α-isopropyl-4α-[(S)-3-methyl-2-(methylamino)butyrylamino]-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14(1),15-tetrene-5,8-dione is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its intricate molecular architecture, which serves as a critical scaffold for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in areas requiring sophisticated chiral building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential drug candidates, especially in oncology and neurology research.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme interactions, receptor binding, and other biological mechanisms due to its complex, drug-like structure.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules in GMP and non-GMP environments.
• Asymmetric Synthesis Building Block: Provides a valuable source of multiple stereocenters for constructing libraries of novel compounds in medicinal chemistry programs.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	(3R,4S,7S)-7β-[(1H-Indol-3-yl)methyl]-3α-isopropyl-4α-[(S)-3-methyl-2-(methylamino)butyrylamino]-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14(1),15-tetrene-5,8-dione
CAS No.	18867-84-0
Molecular Formula	C30H38N4O4
Molecular Weight	518.65 g/mol
Synonyms	7β-(Indol-3-ylmethyl)-3α-isopropyl-4α-[(S)-3-methyl-2-(methylamino)butyrylamino]-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14(1),15-tetrene-5,8-dione; Bicyclic Depsipeptide Intermediate; CAS 18867-84-0; (3R,4S,7S)-Isomer of the Indole-Containing Depsipeptide; 2-Oxa-6,9-diazabicyclo[10.2.2]hexadecatetrene Derivative
EINECS	Contact for details

Quality Control

Our (3R,4S,7S)-7β-[(1H-Indol-3-yl)methyl]-3α-isopropyl-4α-[(S)-3-methyl-2-(methylamino)butyrylamino]-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-10,12,14(1),15-tetrene-5,8-dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided to ensure full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.