Description

2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid is a high-purity, chemically defined steroid derivative with a sulfated and glycine-conjugated structure, making it a critical intermediate for advanced pharmaceutical research and development. Its precise stereochemistry and functional groups are essential for studying steroid hormone metabolism, receptor interactions, and the synthesis of novel therapeutic agents. This compound is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) focused on endocrinology, oncology, and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Biochemical Research: Used as a reference standard or probe in studies of steroid sulfation pathways, enzyme kinetics (sulfotransferases), and metabolic profiling.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for the qualitative and quantitative analysis of complex biological samples.
• Drug Metabolism and Pharmacokinetics (DMPK): Utilized to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of related steroid compounds.
• Preclinical Development: Acts as a starting material or intermediate for producing compounds used in animal model studies for efficacy and toxicity.
• Academic Research: Supports fundamental research in organic chemistry, medicinal chemistry, and steroid biology at universities and government labs.

Basic Information

Product Name	2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
CAS No.	15324-64-8
Molecular Formula	C26H41NO7S
Molecular Weight	511.68 g/mol
Synonyms	Glycine, N-[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-1-oxopentyl]-; 3β-Sulfoxy-5β-cholan-24-oyl glycine; Sulfated glycine-conjugated bile acid derivative; N-[(3β-Sulfooxy-5β-cholan-24-oyl)]glycine; Steroid sulfoglycinate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, supported by advanced analytical techniques including HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability, consistency, and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.