Description

3-Fluoro-1,5-Naphthyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom onto the 1,5-naphthyridine scaffold, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor programs and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for developing novel organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the design of fluorescent tags or molecular probes for studying biological systems and mechanisms.
• Catalyst Ligand Development: The nitrogen-rich structure makes it a candidate for designing novel ligands in transition metal catalysis.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry and structure-activity relationships.

Basic Information

Product Name	3-Fluoro-1,5-Naphthyridine
CAS No.	959617-74-4
Molecular Formula	C8H5FN2
Molecular Weight	148.14 g/mol
Synonyms	1,5-Naphthyridine, 3-fluoro-; 3-Fluoronaphthyridine; 3-Fluoro-1,5-diazanaphthalene; 3-F-1,5-Naph; 959617-74-4; 3-Fluoro[1,5]naphthyridine; 3-Fluoro-1,5-naphthyridin
EINECS	Contact for details

Quality Control

Our 3-Fluoro-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality assurance ensures reliable performance in your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.