Description

8-Fluoroisoquinoline is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis and pharmaceutical research. Its unique structure, featuring a fluorine atom on the isoquinoline scaffold, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to introduce fluorine into target molecules, thereby modulating their biological activity, metabolic stability, and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Precursor: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials requiring fluorinated aromatic systems.
• Ligand and Catalyst Development: Employed in the synthesis of specialized fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine-18 Radiochemistry: A potential precursor for positron emission tomography (PET) tracer development, leveraging the fluorine atom for isotopic labeling.
• Academic and Contract Research: A valuable reagent for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	8-Fluoroisoquinoline
CAS No.	1075-00-9
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	Isoquinoline, 8-fluoro-; 8-Fluoro-isoquinoline; 8-Fluoroisoquinoline; 1-Azanaphthalene, 8-fluoro-; 8-Fluoro-1-azanaphthalene; NSC 406906; 8-Fluoro-isoquinoline; 8-Fluoro-2-azanaphthalene
EINECS	Contact for details

Quality Control

Our 8-Fluoroisoquinoline is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.