Description

2-Hydroxy-6-(Trifluoromethyl)Pyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a hydroxyl group with a trifluoromethyl substituent, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Building block for next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-Hydroxy-6-(Trifluoromethyl)Pyridine
CAS No.	34486-06-1
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	6-(Trifluoromethyl)pyridin-2-ol; 2-Pyridinol, 6-(trifluoromethyl)-; 6-Trifluoromethyl-2-pyridinol; 2-Hydroxy-6-trifluoromethylpyridine; 6-Trifluoromethyl-2-hydroxypyridine; α,α,α-Trifluoro-2-hydroxy-6-picoline; 2-Hydroxy-α,α,α-trifluoro-6-picoline
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are prepared in compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.