Description

2-Fluoro-3-Nitropyridine is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or sensors.
• Chemical Biology Probes: Utilized to create fluorinated probes for studying biological mechanisms and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	2-Fluoro-3-Nitropyridine
CAS No.	1480-87-1
Molecular Formula	C5H3FN2O2
Molecular Weight	142.09 g/mol
Synonyms	3-Nitro-2-fluoropyridine; 2-Fluoro-3-nitropyridine; Pyridine, 2-fluoro-3-nitro-; 2-Fluoropyridine-3-nitropyridine; 1480-87-1; 3-Nitro-2-fluoro-pyridine; 2-Fluoro-3-nitro-pyridine; NSC 404058
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Nitropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nitro-substituted aromatic structure, it should be handled and stored separately from strong reducing agents and combustible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.