Description

2,3-Difluoropyridine is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring two fluorine atoms on the pyridine ring, makes it a critical intermediate for introducing fluorine motifs into complex molecules, thereby modulating their physicochemical and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for fluorine-containing drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability, metabolic stability, and target binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the research and production of fluorinated liquid crystals, organic semiconductors, and polymers with tailored electronic and surface properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and in organic methodology development for new fluorination reactions.

Basic Information

Product Name	2,3-Difluoropyridine
CAS No.	1513-66-2
Molecular Formula	C5H3F2N
Molecular Weight	115.08 g/mol
Synonyms	2,3-Difluoropyridine; Pyridine, 2,3-difluoro-; 2,3-Difluoro-pyridine; 2,3-Difluoropyridine (1513-66-2); 2,3-Difluoropyridine, 98+%; 2,3-Difluoropyridine, 98%; 2,3-Difluoropyridine, 99%; 2,3-Difluoropyridine, 97%
EINECS	Contact for details

Quality Control

Our 2,3-Difluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.