Description

5-Fluoro-1-Methylpyrimidine-2,4(1H,3H)-Dione is a fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs, antiviral agents, and other fluorinated drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, and plant growth regulators that incorporate a fluoropyrimidine moiety.
• Chemical Synthesis: Serves as a versatile fluorinated building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Biochemical Research: Employed in studies investigating enzyme inhibition, metabolic pathways, and as a tool compound in life science research.
• Material Science: Potential intermediate for the synthesis of specialty polymers or organic electronic materials requiring specific fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-1-Methylpyrimidine-2,4(1H,3H)-Dione
CAS No.	155-16-8
Molecular Formula	C5H5FN2O2
Molecular Weight	144.10 g/mol
Synonyms	5-Fluoro-1-methyluracil; 1-Methyl-5-fluorouracil; 5-Fluoro-1-methyl-2,4(1H,3H)-pyrimidinedione; 5-Fluoro-1-methyl-2,4-dihydroxypyrimidine; NSC 38280; 5-F-1-MeU; 1-Methyl-5-FU
EINECS	205-841-3

Quality Control

Our 5-Fluoro-1-Methylpyrimidine-2,4(1H,3H)-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.