Description

5-Fluoropyridine-3-Carboxylic Acid n-Oxide is a high-value, multi-functional heterocyclic building block characterized by its unique pyridine N-oxide core and carboxylic acid functionality. This compound is essential for advanced organic synthesis, enabling the precise introduction of a fluorinated, oxidized pyridine scaffold into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Fluoropyridine-3-Carboxylic Acid n-Oxide
CAS No.	1526-19-8
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	3-Carboxy-5-fluoropyridine 1-Oxide; 5-Fluoronicotinic Acid N-Oxide; 5-Fluoropyridine-3-carboxylic Acid 1-Oxide; 5-Fluoro-3-pyridinecarboxylic Acid N-Oxide; 5-Fluoronicotinic Acid Oxide; 1526-19-8; 5-Fluoro-3-pyridinecarboxylic acid, 1-oxide
EINECS	Contact for details

Quality Control

Our 5-Fluoropyridine-3-Carboxylic Acid n-Oxide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.