Description

3-Fluoro-2-Hydroxypyridine is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters because its unique structure, featuring both a fluorine atom and a hydroxyl group on the pyridine ring, enables precise molecular modifications critical for developing novel active ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluorine moiety can improve activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for biochemical and medicinal research.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluoropyridine scaffolds.

Basic Information

Product Name	3-Fluoro-2-Hydroxypyridine
CAS No.	1547-29-1
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	2-Hydroxy-3-fluoropyridine; 3-Fluoro-2-pyridinol; 3-Fluoro-2(1H)-pyridinone; 2-Fluoro-3-hydroxypyridine; 3-Fluoropyridin-2-ol; 3-Fluoro-1H-pyridin-2-one; 1547-29-1; 3-F-2-OH-Py
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.