Description

3-Amino-2-Fluoropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a fluorine substituent, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce fluorinated motifs into target molecules, thereby modulating their biological activity, stability, and physicochemical characteristics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Used to prepare specialized nitrogen-containing ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate in the creation of fluorinated polymers, liquid crystals, and electronic materials for specialized applications.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and fluorescent tags used in diagnostic and imaging applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and process development.

Basic Information

Product Name	3-Amino-2-Fluoropyridine
CAS No.	1597-33-7
Molecular Formula	C5H5FN2
Molecular Weight	112.11 g/mol
Synonyms	2-Fluoro-3-aminopyridine; 2-Fluoro-3-pyridinamine; 3-Pyridinamine, 2-fluoro-; 2-Fluoropyridin-3-amine; 3-Amino-2-fluoropyridine; 2-Fluoro-3-aminopyridine; 3-Amino-2-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from methods including HPLC, GC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.