Description

7-Fluoro-2-Oxo-1,5-Naphthyridine-1(2H)-Acetaldehyde is a high-value fluorinated naphthyridine derivative, serving as a critical advanced pharmaceutical intermediate (API) for modern drug discovery. Its unique molecular scaffold is engineered to introduce specific bioactivity and metabolic stability into target compounds, making it indispensable for research and development. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutics, particularly in oncology and antiviral domains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and antiviral drugs.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to enhance potency and pharmacokinetic properties of drug candidates.
• Fluorinated Compound Synthesis: Serves as a versatile precursor for introducing the 7-fluoro-naphthyridine moiety into more complex molecular architectures, leveraging fluorine's beneficial effects on bioavailability and binding affinity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	7-Fluoro-2-Oxo-1,5-Naphthyridine-1(2H)-Acetaldehyde
CAS No.	959615-66-8
Molecular Formula	C₁₀H₇FN₂O₂
Molecular Weight	206.17 g/mol
Synonyms	1,5-Naphthyridine-1(2H)-acetaldehyde, 7-fluoro-2-oxo-; 7-Fluoro-2-oxo-1,2-dihydro-1,5-naphthyridine-1-acetaldehyde; 1(2H)-Acetaldehyde, 7-fluoro-2-oxo-1,5-naphthyridine-; 959615-66-8; 7-Fluoronaphthyridine acetaldehyde derivative; Fluorinated naphthyridine aldehyde; 7-Fluoro-1,5-naphthyridone-1-acetaldehyde
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. Production can be aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.