Description

1H-Imidazole-4-Propanoic Acid, 5-Fluoro-, Methyl Ester is a high-value fluorinated imidazole derivative, a crucial synthetic intermediate in advanced organic chemistry. Its core value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the life sciences sector who require specialized building blocks for drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those incorporating fluorinated heterocycles to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the fluorinated imidazole moiety can enhance biological activity and environmental profile.
• Bioconjugation & Probe Synthesis: Utilized in the creation of fluorescent probes, affinity labels, and other biochemical tools for diagnostic and research applications due to its reactive ester group.
• Material Science Precursor: Acts as a monomer or functional additive in the synthesis of specialized polymers and advanced materials with unique electronic or surface properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and fluorine chemistry.

Basic Information

Item	Details
Product Name	1H-Imidazole-4-Propanoic Acid, 5-Fluoro-, Methyl Ester
CAS No.	959293-10-8
Molecular Formula	C7H9FN2O2
Molecular Weight	172.16 g/mol
Synonyms	5-Fluoro-1H-imidazole-4-propanoic acid methyl ester; Methyl 3-(5-fluoro-1H-imidazol-4-yl)propanoate; 5-Fluoro-4-(2-methoxy-2-oxoethyl)-1H-imidazole; Methyl 5-fluoro-1H-imidazole-4-propionate; 959293-10-8; 5-Fluoroimidazole-4-propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-4-Propanoic Acid, 5-Fluoro-, Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure it is stored separately from such materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.