Description

Dgat-1 Inhibitor CAS NO 959122-11-3 is a potent and selective small-molecule inhibitor of diacylglycerol acyltransferase 1 (DGAT1), a key enzyme in triglyceride synthesis. This compound is a critical research tool for investigating lipid metabolism, energy homeostasis, and related metabolic disorders. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic disease, obesity, and diabetes research.

Application

• Biochemical Research: Used as a selective pharmacological tool to study the role of DGAT1 in cellular and systemic lipid metabolism.
• Drug Discovery & Development: Serves as a reference compound or lead molecule in preclinical research for developing novel therapeutics targeting obesity, type 2 diabetes, and NAFLD (Non-Alcoholic Fatty Liver Disease).
• Academic Studies: Enables mechanistic studies in molecular biology and physiology to elucidate pathways of fat absorption, storage, and energy utilization.
• In Vitro Assay Development: Used to validate and calibrate high-throughput screening assays for identifying new DGAT1 inhibitor candidates.
• Metabolic Pathway Analysis: Facilitates target validation and pathway analysis in model organisms and cell-based systems.

Basic Information

Product Name	Dgat-1 Inhibitor
CAS No.	959122-11-3
Molecular Formula	C23H21ClF2N4O3
Molecular Weight	474.89 g/mol
Synonyms	DGAT1 Inhibitor; 2-(4-(4-Amino-7-(3-(trifluoromethyl)phenyl)thieno[3,2-c]pyridin-2-yl)phenyl)acetic acid; 4-[2-[4-(Carboxymethyl)phenyl]-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridin-4-yl]benzoic acid; PF-04620110; T863; A922500; DGAT-1 Inhibitor (PF-04620110)
EINECS	Contact for details

Quality Control

Our Dgat-1 Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.