Description

1-Bromo-3-(3,4,4-Trifluoro-But-3-En-1-Yl)-Benzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a bromo-substituted benzene ring with a reactive trifluorobutene moiety, making it a versatile precursor for constructing complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms and bromine handle can impart desirable properties like weather resistance and targeted activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic electronic materials with tailored properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl and conjugated systems.
• Fluorine Chemistry Exploration: A valuable compound for academic and industrial research focused on introducing and manipulating fluorinated groups in organic molecules.
• Liquid Crystal & OLED Precursor: Potential use in the synthesis of fluorinated components for display and lighting technologies.

Basic Information

Product Name	1-Bromo-3-(3,4,4-Trifluoro-But-3-En-1-Yl)-Benzene
CAS No.	958452-09-0
Molecular Formula	C10H8BrF3
Molecular Weight	265.07 g/mol
Synonyms	3-(1-Bromo-3-phenyl)propyl-3,4,4-trifluoro-1-butene; 1-Bromo-3-(3,4,4-trifluorobut-3-en-1-yl)benzene; 3-(3-Bromophenyl)-1,1,2-trifluoro-1-butene; m-Bromophenyl-3,4,4-trifluorobut-1-ene; 958452-09-0; Benzene, 1-bromo-3-(3,4,4-trifluoro-3-buten-1-yl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(3,4,4-Trifluoro-But-3-En-1-Yl)-Benzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.