Description

2,4-Dibromo-1-Fluorobenzene is a halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms, which allow for selective functionalization and the introduction of complexity into target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or further coupling reactions.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the dibromofluorobenzene moiety contributes to the compound's stability and biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-couplings.
• Material Science Monomer: Employed in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Research & Development: A versatile reagent for exploring novel organic reactions, including nucleophilic aromatic substitution (SNAr) and metal-halogen exchange reactions.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the influence of fluorine atoms on the reactivity and physical properties of aromatic systems.

Basic Information

Product Name	2,4-Dibromo-1-Fluorobenzene
CAS No.	1435-53-6
Molecular Formula	C6H3Br2F
Molecular Weight	253.89 g/mol
Synonyms	1,3-Dibromo-4-fluorobenzene; 4-Fluoro-1,3-dibromobenzene; 2,4-Dibromofluorobenzene; 4-Fluorobenzene-1,3-dibromide; NSC 3775; Fluorobenzene, 2,4-dibromo-; Benzene, 1,3-dibromo-4-fluoro-
EINECS	215-857-4

Quality Control

Our 2,4-Dibromo-1-Fluorobenzene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Related Substances (GC/HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.