Description

1-Fluoro-3-(Pentafluorothio)Benzene, also known as 1-Fluoro-3-(Pentafluorosulphanyl)Benzene, is a high-value fluorinated aromatic building block characterized by the unique pentafluorosulfanyl (SF5) functional group. This compound is essential for introducing the highly electronegative, lipophilic, and thermally stable SF5 moiety into advanced molecular architectures, significantly altering their physical and chemical properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the development of novel active ingredients and specialty polymers with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where the SF5 group can improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Serves as a key precursor for novel herbicides, fungicides, and insecticides, leveraging the SF5 group's ability to enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Incorporated into the core structures of advanced electronic display materials to modify dielectric anisotropy and improve thermal and chemical stability.
• Polymer & Material Science: Acts as a monomer or modifier for creating high-performance polymers with exceptional chemical resistance, low surface energy, and unique optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution to construct complex, fluorinated molecules for research and development.
• Energetic Materials & Propellants: Investigated for use in the development of next-generation high-density, high-performance energetic materials due to the SF5 group's properties.

Basic Information

Product Name	1-Fluoro-3-(Pentafluorothio)Benzene
CAS No.	1422-41-9
Molecular Formula	C6H4F6S
Molecular Weight	222.15 g/mol
Synonyms	1-Fluoro-3-(pentafluorosulfanyl)benzene; 3-Fluorophenylsulfur pentafluoride; 3-Fluoro-1-(pentafluorosulfanyl)benzene; 3-Fluorobenzene, 1-(pentafluorothio)-; 1-Fluoro-3-(pentafluorosulphanyl)benzene; 3-Fluorophenylsulfur pentafluoride; (3-Fluorophenyl)sulfur pentafluoride; Benzene, 1-fluoro-3-(pentafluorothio)-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(Pentafluorothio)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research, process development, and scale-up in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.